Committee

 

I moved from the University of Bristol to become Head of Section of the Centre for Endocrine and Diabetes Sciences at Cardiff University in 2010. Research in my group focuses on two areas of Diabetes and Metabolism, Type 1 diabetes and thyroid disease. I have a particular interest in designing and developing medium and large scale clinical studies to address key issues in translational medicine in these areas. Since 2000 I have been working  in collaboration with Prof Mark Peakman at King’s College London to develop a “diabetes vaccine” to slow or halt the autoimmune process that destroys in the insulin making cells in Type 1 diabetes. We have been developing the approach of Peptide Immunotherapy delivered intradermally to promote tolerance to beta cell antigens without the risks of immunosuppression. A large panel of T cell peptide epitopes recognised by individuals with newly-diagnosed Type 1 diabetes has now been identified and in 2008 we completed a first-in-man phase 1a study with a leading candidate peptide derived from Proinsulin. We are leading on multicentre later phase studies of this approach as well as techniques to optimise the ability of antigen presenting cells in the skin to promote tolerance following peptide administration. We have an interest in optimising the immunotherapy and clinical management of the disfiguring and distressing complication of Graves’ disease know as Thyroid Eye Disease. A large multicentre UK study is underway (www.cirted.org), while at the same time our department is exploring the key role of the orbital pre-adipocyte in the pathogenesis of this disease.

 
 

Student Committee 2019-2020

President

Eva Yuen

“I’ve always wanted to get involved in research because it’s what brings healthcare forward! In particular, I’m intrigued by the way technology is transforming modern medicine and the potential it holds for future advancement.”


Innovation Lead

Felicity RL

“I’m a final year medic and I intercalated in Biomedical Engineering at Imperial College London after my 3rd year. I’m passionate about encouraging medical students to get involved in innovation because medical technology is very likely to become an increasingly important part of our careers. I firmly believe that medics need to be able to collaborate with industry to help create the best technology to improve patient care.”


Projects Lead

Eloise Baxdale

“I’m a final year student and last year I intercalated in Clinical Epidemiology which is when I really started to enjoy research and consider it as a future career prospect. I have particular interests in Public Health and Women’s Health.”


Events Officer

Abdullah Mukit

“Hi I’m Abdullah a 3rd Year Medical Student and Event’s Officer for CUReS. I’m passionate about research and getting the most out of it as Medical Students! It plays a pivotal role on the future of our careers. I am our local ambassador for the National Student Association of Medical Research so I look forward to involving everyone in our upcoming projects too : ) “


Projects Lead

Ky-Leigh Ang

“Hi my name is Ky-Leigh! I’m in my 3rd year of Medicine and the current projects lead for CUREs. I joined CUREs because I believe that research training and experience is not just “nice to have” but a must for doctors in the future. Research training is beneficial for both our professional development and safety of our patients. As projects lead this year, I hope to involve more students in research by planning activities that make it less daunting!”

Communications Lead

Tyler Jones

“I’m a 3rd year medic with a passion for research. I’ve very keen to get as many people involved in research to really highlight how rewarding it can be! I have a particular interest in cancer biology and surgery.”